Treatment frontiers Nature 467, 622 (2010). doi:10.1038/nature09476 Author: Kerri Smith Nature466 (suppl.), S15–S18 (10.1038/466S15a26 August 2010)This Outlook article stated that Addex Pharmaceuticals has mGluR5 modulators in phase II trials for anxiety and depression. The company says that its only disclosed mGluR5 inhibitor in development, ADX48621, will soon
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Nature 467, 622 (2010). doi:10.1038/nature09475 Authors: Paola Scaffidi, Tom Misteli & Marco E. Bianchi Nature418, 191–195 (2002)In this Letter, the volume and page numbers for reference 21 (R
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation Nature 467, 591 (2010). doi:10.1038/nature09385 Authors: Hugo Mouquet, Johannes F.
Translating cancer research into targeted therapeutics Nature 467, 543 (2010). doi:10.1038/nature09339 Authors: J.
U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation Nature 468, 7324 (2010). doi:10.1038/nature09479 Authors: Daisuke Kaida, Michael G. Berg, Ihab Younis, Mumtaz Kasim, Larry N.
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis Nature 468, 7320 (2010). doi:10.1038/nature09495 Authors: Eva Gonzalez-Suarez, Allison P. Jacob, Jon Jones, Robert Miller, Martine P.
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer Nature 468, 7320 (2010). doi:10.1038/nature09387 Authors: Daniel Schramek, Andreas Leibbrandt, Verena Sigl, Lukas Kenner, John A.
Structural basis for semaphorin signalling through the plexin receptor Nature 467, 7319 (2010). doi:10.1038/nature09473 Authors: Terukazu Nogi, Norihisa Yasui, Emiko Mihara, Yukiko Matsunaga, Masanori Noda, Naoya Yamashita, Toshihiko Toyofuku, Susumu Uchiyama, Yoshio Goshima, Atsushi Kumanogoh & Junichi Takagi Semaphorins and their receptor plexins constitute a pleiotropic cell-signalling system that is used in a wide variety of biological processes, and both protein families have been implicated in numerous human diseases
Hundreds of variants clustered in genomic loci and biological pathways affect human height Nature 467, 7317 (2010). doi:10.1038/nature09410 Authors: Hana Lango Allen, Karol Estrada, Guillaume Lettre, Sonja I. Berndt, Michael N.
The genetics of ageing Nature 467, 622 (2010).